Cardiothoracic & vascular anesthesia
The Prognostic Significance of Red Cell Distribution Width in Cardiac Surgery: A Systematic Review and Meta-Analysis
Authors' conclusion
In conclusion, the authors found that elevated preoperative RDW was associated with increased short- and long-term mortality, POAF, and AKI after cardiac surgery.
Study context
- Population
- Patients undergoing cardiac surgery
- Participants
- 48,092 patients · 26 studies
- Comparison
- Elevated vs non-elevated preoperative RDW
- Outcome
- Adverse outcomes after cardiac surgery (elevated preoperative RDW)
Methodological detailsrandom-effects inverse-variance model, metaregression, MEDLINE, Embase, Cochrane Library searched from inception to May 10, 2022
- Random-effects inverse-variance model
- Metaregression
- MEDLINE, Embase, Cochrane Library searched from inception to May 10, 2022
Pooled result
As reported in the abstract
Long-term mortality, pooled HR
1.63
95% CI 1.05–2.52
Short-term mortality, pooled OR
2.16
95% CI 1.21–3.87
Acute kidney injury (AKI), pooled OR
1.30
95% CI 1.19–1.41
Postoperative AF, pooled OR
1.44
95% CI 1.05–1.96
Further pooled results
Neurologic complications
- Some studies suggested a significant association; too few for meta-analysis
Postoperative RDW
- Less consistently reported; could not be meta-analysed
Original publication
The Prognostic Significance of Red Cell Distribution Width in Cardiac Surgery: A Systematic Review and Meta-Analysis. J Cardiothorac Vasc Anesth. Published 20 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →