Cardiothoracic & vascular anesthesia
Association Between Red Cell Distribution Width and Liver Injury after Cardiac and Aortic Aneurysm Surgery with Cardiopulmonary Bypass
Main finding · Postoperative liver injuryResult — go to the resultAdjusted odds ratio 3.25 95% CI 1.10–9.63Authors' conclusion
Preoperative RDW levels are significantly associated with postoperative LI.
Study context
- Population
- Adults who underwent cardiac and aortic aneurysm surgery with CPB at Changhai Hospital in 2021
- Exposure
- High vs lower preoperative RDW
- Outcome
- Postoperative liver injury
Methodological detailssingle-centre, university-affiliated teaching hospital and tertiary referral center
- Single-centre
- University-affiliated teaching hospital and tertiary referral center
Main finding
As reported in the abstract
Adjusted odds ratio
3.25
95% CI 1.10–9.63
P = 0.033
High vs lower preoperative RDW
aOR 3.25 (95% CI 1.10–9.63); P = 0.033
- Postoperative LI observed
- 75 patients (10%)
Observational data: associations, not effects.
Further findings
Survival · 30 days · log-rank test · Kaplan-Meier analysis
P < 0.001
RDW–LI association by gender (subgroup)
- Men had a higher correlation with LI
- p for interaction = 0.041
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association Between Red Cell Distribution Width and Liver Injury after Cardiac and Aortic Aneurysm Surgery with Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. Published 8 September 2024. doi:10. 1053/ j. jvca. 2024. 09. 004
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