Cardiothoracic & vascular anesthesia

Association Between Red Cell Distribution Width and Liver Injury after Cardiac and Aortic Aneurysm Surgery with Cardiopulmonary Bypass

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Main finding · Postoperative liver injuryResult — go to the resultAdjusted odds ratio 3.25 95% CI 1.10–9.63

Authors' conclusion

Preoperative RDW levels are significantly associated with postoperative LI.

Study context

Population
Adults who underwent cardiac and aortic aneurysm surgery with CPB at Changhai Hospital in 2021
Exposure
High vs lower preoperative RDW
Outcome
Postoperative liver injury
Methodological detailssingle-centre, university-affiliated teaching hospital and tertiary referral center
  • Single-centre
  • University-affiliated teaching hospital and tertiary referral center

Main finding

As reported in the abstract

Adjusted odds ratio

3.25

95% CI 1.10–9.63

P = 0.033

High vs lower preoperative RDW
aOR 3.25 (95% CI 1.10–9.63); P = 0.033
Postoperative LI observed
75 patients (10%)

Observational data: associations, not effects.

Further findings

Survival · 30 days · log-rank test · Kaplan-Meier analysis

P < 0.001

RDW–LI association by gender (subgroup)

Men had a higher correlation with LI
  • p for interaction = 0.041

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association Between Red Cell Distribution Width and Liver Injury after Cardiac and Aortic Aneurysm Surgery with Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. Published 8 September 2024. doi:10.1053/j.jvca.2024.09.004

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