Cardiothoracic & vascular anesthesia
The prognostic value of elevated neutrophil–lymphocyte ratio for cardiac surgery‐associated acute kidney injury: A systematic review and meta‐analysis
Pooled result · Postoperative AKI, elevated preoperative NLRResult — go to the resultOdds ratio 1.45 95% CI 1.18–1.77Authors' conclusion
Elevated preoperative NLR is a reliable inflammatory biomarker for predicting AKI following cardiac surgery.
Study context
- Population
- Patients undergoing cardiac surgery
- Participants
- 10,724 patients · 12 studies
- Comparison
- Elevated vs non-elevated perioperative neutrophil-lymphocyte ratio (NLR)
- Outcome
- Postoperative acute kidney injury (AKI)
Methodological detailsmeta-regression
- Meta-regression
Pooled result
Postoperative AKI, elevated preoperative NLR
Odds ratio
1.45
95% CI 1.18–1.77
Elevated vs non-elevated perioperative NLR
OR 1.45 (95% CI 1.18–1.77)
As reported in the abstract
Further pooled results
Postoperative need for renal replacement therapy (RRT), elevated preoperative NLR
| OR (95% CI) | ||
|---|---|---|
| Elevated NLRElevated preoperative NLR | 2.37 (1.50–3.72) | |
| 0.20.5125Odds ratio (log scale) |
Postoperative NLR
- Postoperative NLR measurements not of prognostic significance
Original publication
The prognostic value of elevated neutrophil–lymphocyte ratio for cardiac surgery‐associated acute kidney injury: A systematic review and meta‐analysis. Acta Anaesthesiol Scand. Published 25 November 2022. doi:10.
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