Cardiothoracic & vascular anesthesia
The Relationship Between Transfusion in Cardiac Surgery Patients and Adverse Outcomes
Authors' conclusion
The authors demonstrated a strong independent association between RBC transfusion volume and adverse outcomes after cardiac surgery.
Study context
- Population
- Patients undergoing CABG and/or valvular surgery, single university hospital, July 2014–January 2018
- Participants
- 2,458 patients
- Exposure
- Volume of red blood cell (RBC) transfusion
- Outcome
- Occurrence of an adverse event or prolonged intubation
Methodological detailssingle-centre, multivariate logistic regression
- Single-centre
- Multivariate logistic regression
Main finding
As reported in the abstract
Risk per additional unit of RBC transfused
- Prolonged intubation
- OR 1.493; P < 0.0001
- Infectious composite outcomes
- OR 1.358; P < 0.0001
- Adverse renal outcomes
- OR 1.247; P < 0.0001
- Any adverse event
- OR 1.467; P < 0.0001
Observational data: associations, not effects.
Original publication
The Relationship Between Transfusion in Cardiac Surgery Patients and Adverse Outcomes. J Cardiothorac Vasc Anesth. Published 8 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →