Cardiothoracic & vascular anesthesia
Impact of Red Blood Cell Transfusion on In-hospital Mortality of Isolated Coronary Artery Bypass Graft Surgery: A Retrospective Observational Study of French Nationwide 3-year Cohort
Authors' conclusion
Despite a modest patients' exposure to transfusion, this study suggests that RBC administration is an independent factor of in-hospital mortality in isolated CABG surgery.
Study context
- Population
- Consecutive adults undergoing isolated coronary artery bypass graft (CABG) surgery in France, January 1, 2016, to December 31, 2018
- Participants
- 37,498 adults
- Exposure
- Moderate or massive red blood cell (RBC) transfusion vs no transfusion
- Outcome
- In-hospital mortality rate
Methodological detailsnational database
- National database
Main finding
As reported in the abstract
In-hospital mortality
Each group vs no transfusionOdds ratio (95% CI)P value
Moderate transfusion
1.66(1.27–2.19)
P < 0.001Massive transfusion
6.40(5.07–8.09)
P < 0.001- Overall in-hospital mortality rate
- 1.45%
- Overall RBC transfusion rate
- 9.4%
Observational data: associations, not effects.
Original publication
Impact of Red Blood Cell Transfusion on In-hospital Mortality of Isolated Coronary Artery Bypass Graft Surgery: A Retrospective Observational Study of French Nationwide 3-year Cohort. Ann Surg. Published 28 June 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →