Cardiothoracic & vascular anesthesia
Timing of Blood Transfusions and 30-Day Patient Outcomes After Coronary Artery Bypass Graft Surgery
Authors' conclusion
The authors' data suggested that the postoperative timing of transfusion in patients undergoing coronary artery bypass graft surgery may be associated with an increased incidence of 30-day heart failure and readmission.
Study context
- Population
- Adults undergoing primary CABG at a single tertiary-care academic hospital, January 2014–December 20201,588 (36%) transfused
- Participants
- 2,481 adults
- Exposure
- Timing of RBC transfusion vs no transfusion
- Intraoperativen = 182
- Postoperativen = 489
- Bothn = 222
- Outcome
- 30-day postoperative outcomes
- Follow-up
- 30 days
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
30-day readmission and heart failure
Postoperative vs No transfusionsOdds ratio (CI)P value
Readmission
1.83(1.32–2.54)
P = 0.002Heart failure
1.64(1.2–2.23)
P = 0.008Observational data: associations, not effects.
Original publication
Timing of Blood Transfusions and 30-Day Patient Outcomes After Coronary Artery Bypass Graft Surgery. J Cardiothorac Vasc Anesth. Published 26 November 2022. doi:10.
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