Perioperative medicine & outcomes
The Relevance of Optimal Preoperative Glycemic Control for Outcomes of Patients With Diabetes Undergoing Surgery
Authors' conclusion
Glycemic control significantly impacts morbidity and mortality in surgical patients.
Study context
- Population
- Adults undergoing surgery with recorded HbA1c, American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) 2021–20228 HbA1c/diabetes groups
- Participants
- 502,478 adults
- Exposure
- HbA1c/diabetes categories vs no prediabetes or diabetes
- Outcome
- Postoperative complications
Methodological detailsmulti-institutional registry (ACS-NSQIP 2021-2022), multivariate regression
- Multi-institutional registry (ACS-NSQIP 2021-2022)
- Multivariate regression
Main finding
As reported in the abstract
Postoperative complications (multivariate logistic analysis)
- Undiagnosed prediabetes: lower risk of surgical complications vs no prediabetes or diabetes
- Undiagnosed diabetes: higher risk of medical complications vs no prediabetes or diabetes
- Diagnosed diabetes with near-normal glycemia and with very poor glycemic control: higher odds of any complication
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Prevalence of diabetes categories% of total | Undiagnosed prediabetes 18.1% · Undiagnosed diabetes 5.1% · Diabetes, HbA1c <6% 5.5% · Diabetes, HbA1c 6-6.9% 12.7% · Diabetes, HbA1c 7% to 7.9% 9.1% · Diabetes, HbA1c 8% to 8.9% 4.0% · Diabetes, HbA1c ≥9% 4.6% |
- Prevalence of diabetes categories — Diagnosed diabetes
- 179,697 (35.8%)
- Prevalence of diabetes categories — No diabetes diagnosis
- 322,781 (64.2%)
- Prevalence of diabetes categories — Undiagnosed prediabetes or diabetes
- 23%
Transfusion
- Significantly lower chances with undiagnosed prediabetes and undiagnosed diabetes
Hospital LOS
- Significantly longer with undiagnosed diabetes and diagnosed diabetes with near-normal glycemia, suboptimal or very poor glycemic control vs no prediabetes or diabetes
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Relevance of Optimal Preoperative Glycemic Control for Outcomes of Patients With Diabetes Undergoing Surgery. Ann Surg. Published 12 February 2025. doi:10. 1097/ sla. 0000000000006664
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