Perioperative medicine & outcomes

The Relevance of Optimal Preoperative Glycemic Control for Outcomes of Patients With Diabetes Undergoing Surgery

Ann SurgPublished Retrospective cohort study

Authors' conclusion

Glycemic control significantly impacts morbidity and mortality in surgical patients.

Study context

Population
Adults undergoing surgery with recorded HbA1c, American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) 2021–20228 HbA1c/diabetes groups
Participants
502,478 adults
Exposure
HbA1c/diabetes categories vs no prediabetes or diabetes
Outcome
Postoperative complications
Methodological detailsmulti-institutional registry (ACS-NSQIP 2021-2022), multivariate regression
  • Multi-institutional registry (ACS-NSQIP 2021-2022)
  • Multivariate regression

Main finding

As reported in the abstract

Postoperative complications (multivariate logistic analysis)
  • Undiagnosed prediabetes: lower risk of surgical complications vs no prediabetes or diabetes
  • Undiagnosed diabetes: higher risk of medical complications vs no prediabetes or diabetes
  • Diagnosed diabetes with near-normal glycemia and with very poor glycemic control: higher odds of any complication

Observational data: associations, not effects.

Further findings

OutcomeValues
Prevalence of diabetes categories% of totalUndiagnosed prediabetes 18.1% · Undiagnosed diabetes 5.1% · Diabetes, HbA1c <6% 5.5% · Diabetes, HbA1c 6-6.9% 12.7% · Diabetes, HbA1c 7% to 7.9% 9.1% · Diabetes, HbA1c 8% to 8.9% 4.0% · Diabetes, HbA1c ≥9% 4.6%
Prevalence of diabetes categories — Diagnosed diabetes
179,697 (35.8%)
Prevalence of diabetes categories — No diabetes diagnosis
322,781 (64.2%)
Prevalence of diabetes categories — Undiagnosed prediabetes or diabetes
23%

Transfusion

Significantly lower chances with undiagnosed prediabetes and undiagnosed diabetes

Hospital LOS

Significantly longer with undiagnosed diabetes and diagnosed diabetes with near-normal glycemia, suboptimal or very poor glycemic control vs no prediabetes or diabetes

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The Relevance of Optimal Preoperative Glycemic Control for Outcomes of Patients With Diabetes Undergoing Surgery. Ann Surg. Published 12 February 2025. doi:10.1097/sla.0000000000006664

Composed by AI from the published abstract and checked against it. How Briefs are made →

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