Total intravenous or inhalational volatile anaesthesia and survival after colorectal cancer surgery: a Swedish national registry study
Authors' conclusion
We found no association between the choice of agent for maintenance of anaesthesia and long-term survival outcomes in patients with colorectal cancer.
Study context
- Population
- Patients with stage 1–3 colorectal cancer who underwent resection surgery under GA in Sweden, 2014–20198,161 colon, 3437 rectal cancer
- Participants
- 11,598 patients
- Exposure
- Propofol vs Inhalational volatile anaesthetic agent
- Propofoln = 2,346
- Inhalational volatile anaesthetic agentn = 9,252reference
- Outcome
- Overall survival
Methodological detailsnational registry, 1:2 propensity score matching
- National registry
- 1:2 propensity score matching
Main finding
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Disease-free survival
- No significant difference in either type of cancer
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Total intravenous or inhalational volatile anaesthesia and survival after colorectal cancer surgery: a Swedish national registry study. Anaesthesia. Published 16 December 2024. doi:10.
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