Transfusion of Fresh Frozen Plasma and Platelets in Critically Ill Adults: An American College of Chest Physicians Clinical Practice Guideline

In critically ill patients with thrombocytopenia or coagulopathy, providers should make a risk/benefit assessment before transfusing platelets or fresh frozen plasma (FFP)

Given known transfusion risks and limited data on benefit, most patients will benefit from avoiding platelet or FFP transfusion

In patients at high risk of bleeding, or where a bleeding complication may be catastrophic, transfusion should be considered