Trends in Renal Dysfunction, Renal Replacement Therapy, and Mortality in Intensive Care Units: A Nationwide Japanese ICU database study
Authors' conclusion
In this nationwide Japanese ICU cohort, RRT use among patients with renal dysfunction changed little over the past decade. Although adjusted mortality was lower in some later years, overall temporal changes were modest.
Study context
- Population
- Adult ICU patients, Japanese Intensive Care Patient Database, April 2015–March 2023
- Participants
- 80,255 patients
- Exposure
- April 2015-March 2018 vs April 2018-March 2021 vs April 2021-March 2023
- Outcome
- Adjusted hospital mortality over time
Methodological detailsnationwide database, multivariable mixed-effects logistic regression
- Nationwide database
- Multivariable mixed-effects logistic regression
Main finding
As reported in the abstract
Adjusted hospital mortality
- Adjusted hospital mortality lower in several later years vs 2015; differences between predefined study periods modest
Observational data: associations, not effects.
Further findings
Renal dysfunction
- Proportion with renal dysfunction increased modestly over time
Renal replacement therapy (RRT) utilization
- Overall RRT utilization relatively stable across study periods
Original publication
Trends in Renal Dysfunction, Renal Replacement Therapy, and Mortality in Intensive Care Units: A Nationwide Japanese ICU database study. Anaesth Crit Care Pain Med. Published 24 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →