Tunneled, Noncuffed, Central Venous Catheters: High Success Rates When Used in Children Less Than 2 Years for Intravenous Antibiotics
Authors' conclusion
Success rates for tncCVCs when used in infants to complete a median of 13 days of antibiotic therapy on a single device appear acceptable.
Study context
- Population
- Patients less than 2 years old receiving intravenous antibioticsdevices in 311 patients
- Participants
- 331 participants
- Outcome
- Success rate in completing prescribed treatment with the device
Methodological detailssingle-centre, 6-year, 55 different proceduralists inserted the devices
- Single-centre
- 6-year
- 55 different proceduralists inserted the devices
Main finding
As reported in the abstract
Success in completing prescribed treatment with the device
Success rate
94.9%
Failures
17
Observational data: associations, not effects.
Further findings
CVC dwell time
- Median CVC dwell time, days (IQR 9.2-18.2)
- 13
Outpatient antibiotic therapy
- Patients receiving outpatient antibiotic therapy
- 79%
Predictors of failure
- Any history of previous CVC insertion: more likely to have failed devices
- All neonatal patient devices successfully completed treatment
Safety
- Failures due to accidental dislodgement
- 13
- Of all comers
- 3.9%
- Of failures
- 77%
Original publication
Tunneled, Noncuffed, Central Venous Catheters: High Success Rates When Used in Children Less Than 2 Years for Intravenous Antibiotics. Paediatr Anaesth. Published 4 February 2026. doi:10.
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