Cardiothoracic & vascular anesthesia
Use of Preoperative Natriuretic Peptide in Predicting Mortality After Coronary Artery Bypass Grafting: A Systematic Review and Meta-analysis
Pooled result · Mortality after CABGResult — go to the resultOdds ratio 3.96 95% CI 2.41–6.52Authors' conclusion
Preoperative BNP level is a powerful predictor of mortality in patients undergoing CABG.
Study context
- Population
- Patients undergoing coronary artery bypass grafting (CABG)11 studies
- Comparison
- Elevated vs normal preoperative natriuretic peptide levels
- Outcome
- Short- and long-term mortality after CABG
Methodological detailsrandom effect model, 53 articles retrieved; 11 in qualitative synthesis, 4 in meta-analysis
- Random effect model
- 53 articles retrieved; 11 in qualitative synthesis, 4 in meta-analysis
Pooled result
Mortality after CABG
Odds ratio
3.96
95% CI 2.41–6.52
P < 0.00001
Elevated BNP/NT-proBNP vs Normal
OR 3.96 (95% CI 2.41–6.52); P < 0.00001
As reported in the abstract
Further pooled results
Cut-off values across studies
pg/mL
- Median BNP cut-off (25th-75th percentile 95-324.25 pg/mL)
- 145.5
- Mean NT-proBNP value (± 372 pg/mL)
- 765
Original publication
Use of Preoperative Natriuretic Peptide in Predicting Mortality After Coronary Artery Bypass Grafting: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 20 April 2023. doi:10.
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