Respiratory failure & ventilation
The use of prone position ventilation in Danish patients with COVID‐19‐induced severe acute respiratory distress syndrome treated with veno‐venous extracorporeal membrane oxygenation: A nationwide cohort study with focus on pulmonary effects
Authors' conclusion
Eighty percent of patients responded positively during a PPV session, but this was not associated with overall pulmonary improvement. On a single patient level, responses were heterogenous and only 45% of sessions resulted in clinical improvement. Response in dynamic compliance was associated with starting values of compliance.
Study context
- Population
- COVID-19 patients in Denmark with severe Adult Respiratory Distress Syndrome (ARDS) needing V–V ECMO support, March 2020 - December 202144 treated with PPV
- Participants
- 68 patients
- Outcome
- Response to PPV sessions
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
- Positive clinical response, patients
- 80%
- Positive clinical response, sessions
- 45%
- Increased compliance, sessions
- 38%
- Increased oxygenation, sessions
- 15%
- Number of PPV sessions
- 220
Observational data: associations, not effects.
Further findings
Predictors of response
- Higher dynamic compliance at start of PPV session associated with lower delta change in dynamic compliance during PPV
- Response to a PPV session not predicted by response in prior session
- Dynamic compliance did not change during the ECMO course
Original publication
The use of prone position ventilation in Danish patients with COVID‐19‐induced severe acute respiratory distress syndrome treated with veno‐venous extracorporeal membrane oxygenation: A nationwide cohort study with focus on pulmonary effects. Acta Anaesthesiol Scand. Published 26 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →