Using the TI.VA algorithm to titrate the depth of general anaesthesia: a first-in-humans study
Authors' conclusion
The TI.VA algorithm provides adequate control of clinical anaesthesia.
Study context
- Population
- Patients with breast cancer scheduled for surgery
- Participants
- 9 patients
- Outcome
- Algorithm performance (performance errors; acceptable target GSBIS <50)
Methodological detailssingle-group
- Single-group
Main finding
As reported in the abstract
GSBIS below cut-off of 50
- All patients presented a GSBIS below the cut-off value of 50
- 3417 monitoring points, 285 min of surgery analysed
Observational data: associations, not effects.
Further findings
Intraoperative recall
- None of the patients recalled any intraoperative event
- 0
Safety
- All nine procedures completed without any adverse events
- 0
Original publication
Using the TI.VA algorithm to titrate the depth of general anaesthesia: a first-in-humans study. BJA Open. Published 16 June 2023. doi:10. 1016/ j. bjao. 2023. 100203
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