Anesthetic drugs & techniques

Using the TI.VA algorithm to titrate the depth of general anaesthesia: a first-in-humans study

BJA OpenPublished Prospective first-in-humans study

Authors' conclusion

The TI.VA algorithm provides adequate control of clinical anaesthesia.

Study context

Population
Patients with breast cancer scheduled for surgery
Participants
9 patients
Outcome
Algorithm performance (performance errors; acceptable target GSBIS <50)
Methodological detailssingle-group
  • Single-group

Main finding

As reported in the abstract

GSBIS below cut-off of 50
  • All patients presented a GSBIS below the cut-off value of 50
  • 3417 monitoring points, 285 min of surgery analysed

Observational data: associations, not effects.

Further findings

Intraoperative recall

None of the patients recalled any intraoperative event
0

Safety

All nine procedures completed without any adverse events
0

Original publication

Using the TI.VA algorithm to titrate the depth of general anaesthesia: a first-in-humans study. BJA Open. Published 16 June 2023. doi:10.1016/j.bjao.2023.100203

Composed by AI from the published abstract and checked against it. How Briefs are made →

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