Hemodynamics, fluids & transfusion
Vasoconstriction with phenylephrine increases cardiac output in preload dependent patients
Authors' conclusion
Infusion of phenylephrine during preload dependency increased venous return abolishing preload dependency as evaluated by SVV and increased cardiac stroke volume and -output as measured by indicator-dilution technique.
Study context
- Population
- Patients undergoing General Anaesthesia (GA) for gastrointestinal surgerycrossover, every patient in every phase
- Participants
- 20 patients
- Comparison
- Phenylephrine (PE) infusion during head-up tilt (HUT)-induced preload dependency vs HUT alone and baseline
- Outcome
- SVV, cardiac index (CI) and SVI across phases
Main finding
As reported in the abstract
- All differences significant
- p < 0,001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Vasoconstriction with phenylephrine increases cardiac output in preload dependent patients. J Clin Monit Comput. Published 21 June 2024. doi:10.
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