Cardiothoracic & vascular anesthesia

Venous Thromboembolism Chemoprophylaxis Adherence Rates After Major Cancer Surgery

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

These findings indicate the overall VTE rate after cancer surgery within the VHA is low, VHA inpatient chemoprophylaxis rates are high, and postdischarge VTE chemoprophylaxis prescribing is similar to that of non-VHA health systems.

Study context

Population
Veterans aged 41 years or older without preexisting bleeding disorders or anticoagulation who underwent inpatient cancer surgery (general surgery, thoracic surgery or urology), 101 Veterans Health Administration (VHA) hospitals, 2015–2022
Participants
30,039 veterans · 101 VHA hospitals
Exposure
General surgery vs Urology
  • General surgeryn = 10,301
  • Urologyn = 17,089
Outcome
Postoperative VTE events and VTE chemoprophylaxis adherence
Follow-up
30 days
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Postoperative VTE
Overall postoperative venous thromboembolism (VTE) (385 patients)
1.3%
VTE diagnosed during inpatient hospitalization (199 patients)
0.7%
VTE diagnosed postdischarge (186 patients)
0.6%
Inpatient chemoprophylaxis ordered (24 139 patients)
80.4%
Postdischarge chemoprophylaxis received (3142 patients), with notable variation by specialty
10.5%

Observational data: associations, not effects.

Further findings

Inpatient chemoprophylaxis ordering by specialty · highest for general surgery, lowest for urology

Original publication

Venous Thromboembolism Chemoprophylaxis Adherence Rates After Major Cancer Surgery. JAMA Netw Open. Published 5 September 2023. doi:10.1001/jamanetworkopen.2023.35311

Composed by AI from the published abstract and checked against it. How Briefs are made →

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