Cardiothoracic & vascular anesthesia

A Systematic Review and Meta-Analysis of Local-Regional versus General Anesthesia for Elective Endovascular Abdominal Aortic Aneurysm Repair

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis of observational studies

Pooled result · MortalityResult — go to the resultOdds ratio 0.75 95% CI 0.59–0.97

Authors' conclusion

LRA may offer better outcomes than GA in elective EVAR, including lower mortality, MACE, and shorter HS.

Study context

Population
Patients undergoing elective endovascular abdominal aortic aneurysm repair (endovascular aneurysm repair (EVAR))
Participants
91,560 patients · 17 studies
Comparison
Local-regional anesthesia (LRA) vs general anesthesia (GA) for elective EVAR
Outcome
Mortality
Methodological detailsfixed-effects model, GRADE certainty assessment
  • Fixed-effects model
  • GRADE certainty assessment

Pooled result

As reported in the abstract

Odds ratio

0.75

95% CI 0.59–0.97

LRA vs GA
OR 0.75 (95% CI 0.59–0.97)

Further pooled results

Sensitivity analyses

Most results confirmed; mortality lost significance in some cases

Original publication

A Systematic Review and Meta-Analysis of Local-Regional versus General Anesthesia for Elective Endovascular Abdominal Aortic Aneurysm Repair. J Cardiothorac Vasc Anesth. Published 4 April 2025. doi:10.1053/j.jvca.2025.03.045

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