Cardiothoracic & vascular anesthesia

Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery

J Cardiothorac Vasc AnesthPublished Mechanistic study

Authors' conclusion

Early alterations in microvascular reactivity, evaluated by a skin thermal challenge, are correlated with organ dysfunction.

Study context

Population
Patients admitted to the ICU post-cardiac surgery
Participants
46 patients
Comparison
Slow recovery vs rapid recovery after cardiac surgery
  • Slow recoveryn = 14
  • Rapid recoveryn = 32reference
Outcome
SBF ratio (43°C/37°C)
Methodological detailsnoninvasive physiological study, single-centre
  • Noninvasive physiological study
  • Single-centre

Main finding

As reported in the abstract

Slow recovery

2.8

range 1.5–4.7

Rapid recovery

4.8

range 3.7–7.8

P < 0.01

Further findings

OutcomeSlow recoveryRapid recoveryP value
SBF after 9 minutes at 43°C48.5 (range 17.3–69.0)85.1 (range 45.2–125.7)P < 0.01

Skin blood flow (SBF) at 37°C

Not significantly different between slow and rapid recovery

Dysfunction of at least one organ (SOFA) by SBF ratio tertile (lowest, middle, highest) · 48 hours post-cardiac surgery

Lowest tertile
88%
Middle tertile
40%
Highest tertile
27%
P across tertiles
P < 0.01

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 4 July 2024. doi:10.1053/j.jvca.2024.06.045

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