Cardiothoracic & vascular anesthesia
Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery
Authors' conclusion
Early alterations in microvascular reactivity, evaluated by a skin thermal challenge, are correlated with organ dysfunction.
Study context
- Population
- Patients admitted to the ICU post-cardiac surgery
- Participants
- 46 patients
- Comparison
- Slow recovery vs rapid recovery after cardiac surgery
- Slow recoveryn = 14
- Rapid recoveryn = 32reference
- Outcome
- SBF ratio (43°C/37°C)
Methodological detailsnoninvasive physiological study, single-centre
- Noninvasive physiological study
- Single-centre
Main finding
As reported in the abstract
Slow recovery
2.8
range 1.5–4.7
Rapid recovery
4.8
range 3.7–7.8
P < 0.01
Further findings
| Outcome | Slow recovery | Rapid recovery | P value |
|---|---|---|---|
| SBF after 9 minutes at 43°C | 48.5 (range 17.3–69.0) | 85.1 (range 45.2–125.7) | P < 0.01 |
Skin blood flow (SBF) at 37°C
- Not significantly different between slow and rapid recovery
Dysfunction of at least one organ (SOFA) by SBF ratio tertile (lowest, middle, highest) · 48 hours post-cardiac surgery
- Lowest tertile
- 88%
- Middle tertile
- 40%
- Highest tertile
- 27%
- P across tertiles
- P < 0.01
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 4 July 2024. doi:10. 1053/ j. jvca. 2024. 06. 045
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