Respiratory failure & ventilation

An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline

Am J Respir Crit Care MedPublished Clinical practice guideline

Methodological detailsGRADE framework, multidisciplinary panel
  • GRADE framework
  • Multidisciplinary panel

Recommendations

As issued by the authors

  1. conditional recommendation, moderate certainty of evidence

    We suggest corticosteroids for patients with acute respiratory distress syndrome (ARDS)

  2. conditional recommendation, low certainty of evidence

    We suggest venovenous ECMO in selected patients with severe ARDS

  3. conditional recommendation, low certainty of evidence

    We suggest neuromuscular blockers in patients with early severe ARDS

  4. conditional recommendation, low to moderate certainty

    We suggest higher positive end-expiratory pressure (PEEP) without lung recruitment maneuvers vs lower PEEP in patients with moderate to severe ARDS

  5. strong recommendation, moderate certainty

    We recommend against prolonged lung recruitment maneuvers in patients with moderate to severe ARDS

Original publication

An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. Published 1 January 2024. doi:10.1164/rccm.202311-2011st

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