Anterior peri-iliopsoas muscle space block for analgesia in lower-limb orthopedic surgery: A randomized controlled trial
Authors' conclusion
PIMSB using a single skin puncture was associated with lower opioid requirements and lower postoperative pain scores after unilateral orthopedic procedures involving the knee region.
Study context
- Population
- Patients undergoing unilateral orthopedic procedures involving the knee region
- Participants
- 56 patients
- Comparison
- Preoperative peri-iliopsoas muscle space block (PIMSB) followed by general anesthesia (GA) vs GA only
- Primary endpoint
- Cumulative postoperative morphine consumption
- Follow-up
- First 24 h
Methodological detailsprospective
- Prospective
Primary result
As reported in the abstract
Between-group difference
10.5 mg
95% CI 9.28–11.78
P < 0.001
By group
PIMSB vs Control
between-group difference 10.5 mg (95% CI 9.28–11.78); P < 0.001
Secondary outcomes
Mean, μg
| Outcome | PIMSB | Control | Between-group difference (μg) (95% CI) | P value | |
|---|---|---|---|---|---|
| Intraoperative fentanyl consumption | 166.4 (SD 20.1) | 241.1 (SD 24.1) | 74.7 (62.82–86.58) | P < 0.001 | |
| −50050100Difference, μg (linear scale) |
Preoperative numerical rating score (NRS) · 30 min after PIMSB
- Preoperative NRS significantly decreased after the block
Postoperative surgical-site pain (NRS) · within 24 h
- Notable differences between PIMSB and nonblock groups
Perfusion index in the operative limb · 10, 20 and 30 min after the block
- Significantly higher after PIMSB and continued to increase during monitoring
Original publication
Anterior peri-iliopsoas muscle space block for analgesia in lower-limb orthopedic surgery: A randomized controlled trial. J Clin Anesth. Published 7 June 2026. doi:10.
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