Hemodynamics, fluids & transfusion
Apnea Testing Practice to Increase Baseline PaCO2 and Frequency of Blood Gas Analyses
Authors' conclusion
Increasing the baseline PaCO2 and doing more blood gas analyses can significantly shorten the time needed for AT and improve the AT positivity rate.
Study context
- Population
- Patients undergoing apnea testing (AT), with blood gas analysis at 3, 5 and 8 minutes
- Participants
- 55 patients
- Exposure
- Initial PaCO2 ≥40 mmHg vs <40 mmHg before apnea testing
- Experimentaln = 27
- Controln = 28reference
- Outcome
- Time to reach target PaCO2
Methodological detailsmulticentre, seven teaching hospitals
- Multicentre
- Seven teaching hospitals
Main finding
As reported in the abstract
P = 0.001
- AT positivity rate
- 100%
Observational data: associations, not effects.
Further findings
Target PaCO2 reached within 5 minutes
P = 0.001
Initial PaCO2
Safety
Hypotension · no statistical difference
P = 0.245
- Hypotension — Unable to complete 8-minute disconnection due to hypotension (overall)
- 7 (12.7%)
Original publication
Apnea Testing Practice to Increase Baseline PaCO2 and Frequency of Blood Gas Analyses. J Cardiothorac Vasc Anesth. Published 21 December 2023. doi:10.
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