Respiratory failure & ventilation
Application of high-flow nasal oxygen during anesthesia induction for frame-based stereoelectroencephalography: a randomized controlled non-inferiority trial
Primary result · Lowest SpO2Result — go to the resultMedian difference 1 % 95 CI 0–2%Authors' conclusion
HFNO is non-inferior to facemask ventilation in maintaining oxygenation during anesthesia induction for frame-based SEEG.
Study context
- Population
- Adults with refractory epilepsy undergoing frame-based stereoelectroencephalography (SEEG)
- Participants
- 46 adults
- Comparison
- High-flow nasal oxygen (HFNO) vs facemask ventilation during anesthesia induction
- Primary endpoint
- Lowest SpO2
Methodological detailsnon-inferiority
- Non-inferiority
Primary result
As reported in the abstract
Median difference
1 %
95 CI 0–2%
By group
HFNO vs Facemask
median difference 1 % (95 CI 0–2%)
Secondary outcomes
Post-intubation PaO2
| Outcome | HFNO | Facemask | P value |
|---|---|---|---|
| Airway adjuncts use | 0/23 | 6/23 | P = 0.022 |
| Time to secure the airwayShortened with HFNO | P = 0.015 | ||
| Anesthesiologist satisfaction and patient comfortBoth improved with HFNO | P < 0.0001 |
Post-intubation PaO2
- Significantly higher in HFNO
Hemodynamic parameters and first-pass intubation success
- Similar between groups
Original publication
Application of high-flow nasal oxygen during anesthesia induction for frame-based stereoelectroencephalography: a randomized controlled non-inferiority trial. Perioper Med (Lond). Published 5 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →