Hemodynamics, fluids & transfusion
Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis
Authors' conclusion
During LBNP-induced hypovolemia, there were reciprocal changes in UL&LL bioimpedance. These changes reflected hemodynamic compensatory mechanisms to hypovolemia.
Study context
- Population
- Healthy volunteers undergoing gradual Lower body negative Pressure (LBNP)-induced hypovolemia (baseline, −15, −30, −45, −60 mmHg, recovery at −30 mmHg and baseline)
- Participants
- 26 healthy volunteers
- Outcome
- Changes in upper (UL) and lower (LL) extremity bioimpedance during LBNP-induced hypovolemia
Main finding
As reported in the abstract
UL and LL bioimpedance during LBNP-induced hypovolemia
Correlation of estimated blood loss with UL bioimpedance (R)
0.97
Correlation of estimated blood loss with LL bioimpedance (R)
- 0.97
Observational data: associations, not effects.
Further findings
UL and LL bioimpedance during recovery phases
- Significant increase in LL bioimpedance and reduction in UL bioimpedance
Original publication
Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis. J Clin Monit Comput. Published 15 November 2023. doi:10. 1007/ s10877-023-01098-y
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