Respiratory failure & ventilation
The Association Between Mechanical Power and Mortality in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Systematic Review and Meta-Analysis
Pooled result · Mechanical powerResult — go to the resultMD 1.91 J/min 95% CI 1.30–2.51Authors' conclusion
Higher mechanical power was consistently associated with increased mortality in invasively ventilated adults.
Study context
- Population
- Adult critically ill patients receiving invasive mechanical ventilation34 studies
- Comparison
- Mechanical power in nonsurvivors vs survivors
- Outcome
- Association between mechanical power and mortality
Methodological detailsrandom-effects models
- Random-effects models
Pooled result
Mechanical power
MD
1.91 J/min
95% CI 1.30–2.51
Nonsurvivors vs Survivors
MD 1.91 J/min (95% CI 1.30–2.51)
As reported in the abstract
Further pooled results
| Outcome | MD (J/min/kg) (95% CI) | |
|---|---|---|
| Mechanical power normalized to predicted body weight | 0.06 (0.04–0.08) | |
| −0.0500.050.1Difference, J/min/kg (linear scale) |
| Outcome | MD (J/min/mL/cm H 2 O) (95% CI) | |
|---|---|---|
| Mechanical power normalized to respiratory system compliance | 0.28 (0.10–0.45) | |
| −0.200.20.40.6Difference, J/min/mL/cm H 2 O (linear scale) |
| Outcome | Estimate | |
|---|---|---|
| Mortality per 1 J/min increase in mechanical power (adjusted)Per 1 J/min increase | aOR 1.04 (95% CI 1.03–1.06) | |
| Mortality per 1 J/min increase in mechanical power (adjusted)Per 1 J/min increase | aHR 1.03 (95% CI 1.00–1.07) | |
| 0.512Ratio (log scale) |
Mortality with mechanical power threshold >17 J/min
| OR (95% CI) | ||
|---|---|---|
| Mechanical power >17 J/minAbstract prints "threshold older than 17 J/min" | 1.60 (1.34–1.91) | |
| 0.512Odds ratio (log scale) |
Original publication
The Association Between Mechanical Power and Mortality in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Systematic Review and Meta-Analysis. Crit Care Med. Published 18 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →