Cardiothoracic & vascular anesthesia
Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity
Authors' conclusion
The timing of decrease (after CPB or end of surgery) may provide hints regarding the injury pathophysiology and its onset.
Study context
- Population
- Adults without documented previous stroke undergoing cardiac surgery with cardiopulmonary bypass (CPB), single university hospital, July 2016–January 2018
- Participants
- 803 adults
- Exposure
- Change in EEG lateral interconnection ratio (LIR) in patients with postoperative stroke or delirium vs no documented neurologic complications
- Stroken = 31
- Deliriumn = 48
- No-dysfunctionn = 724reference
- Outcome
- Decrease in intraoperative LIR index (median [IQR]; valid EEG samples)
Methodological detailssingle-centre
- Single-centre
Further findings
| Outcome | Stroke | Delirium | No-dysfunction | P value |
|---|---|---|---|---|
| Decrease in LIR from surgery start to post-CPB period: Stroke vs No-dysfunctionMedian | 0.08 (IQR 0.01–0.36) | −0.04 (IQR −0.13–0.04) | P < 0.0001 | |
| Valid EEG samples | 21 | — not stated in the abstract | 551 | |
| Decrease in LIR from surgery start to surgery end: Delirium vs No-dysfunctionMedian | 0.15 (IQR 0.02–0.30) | −0.02 (IQR −0.12–0.08) | p ≈ 0.001 | |
| Valid EEG samples | — not stated in the abstract | 12 | 376 |
— not stated in the abstract
Original publication
Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity. J Cardiothorac Vasc Anesth. Published 25 May 2023. doi:10.
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