Cardiothoracic & vascular anesthesia
Association Between Single-Injection Regional Analgesia and Postoperative Pain in Cardiac Surgery Patients: A Single-Center Retrospective Cohort Study
Authors' conclusion
In this retrospective study, the implementation of single-shot chest wall nerve blocks with liposomal bupivacaine was not associated with decreased postoperative pain scores or opioid consumption at 72 hours in select cardiac surgical patients at one institution.
Study context
- Population
- Adults undergoing cardiothoracic surgery at a Midwestern academic hospital, July 1, 2020–June 30, 2022
- Participants
- 1,038 adults
- Exposure
- Nerve block vs No nerve block
- Nerve blockn = 301
- No nerve blockn = 737reference
- Outcome
- Mean postoperative pain scores
- Follow-up
- 12 ± 2, 24 ± 4, 48 ± 8 and 72 ± 12 hours
Methodological detailssingle-centre, adjusted analysis, Bilateral parasternal intercostal plane blocks in 294 [98%]; performed after induction and before incision in 280 [93%]
- Single-centre
- Adjusted analysis
- Bilateral parasternal intercostal plane blocks in 294 [98%]; performed after induction and before incision in 280 [93%]
Main finding
As reported in the abstract
- Not significantly different between groups at all time points (adjusted)
- Adjusted for age, gender, ASA status, select comorbidities, surgical procedure type
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Mean opioid requirements (MME) · 72 hours | P = 0.195 |
- Mean opioid requirements (MME): 68.6 [95% CI, 56.3-83.4] vs 62.9 [95% CI, 52.8-74.9]
- Mean opioid requirements (MME): adjusted for age, gender, ASA status, select comorbidities, surgical procedure type
Mean opioid requirements (MME) · 72 hours
- No difference in mean opioid requirements at 72 h between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association Between Single-Injection Regional Analgesia and Postoperative Pain in Cardiac Surgery Patients: A Single-Center Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 2 July 2024. doi:10.
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