Hemodynamics, fluids & transfusion
Association Between Storage Time of Transfused Red Blood Cells and Infection After Clean-contaminated Surgery: A Retrospective Cohort Study
Authors' conclusion
Prolonged storage time of transfused RBCs was not associated with increased risks of infections after clean-contaminated surgery.
Study context
- Population
- Adults undergoing clean-contaminated surgery 2014–2018 who received allogeneic RBC transfusion
- Participants
- 4,046 adults · 11,604 transfusion episodes
- Exposure
- Longer vs shorter storage time of transfused red blood cells (RBCs)
- Outcome
- Infections developing after transfusion
- Follow-up
- Within POD 30
Methodological detailstransfusion episode-level and patient-level analyses, adjusted for 17 confounders
- Transfusion episode-level and patient-level analyses
- Adjusted for 17 confounders
Main finding
As reported in the abstract
Postoperative infection
Estimate (95% CI)
Storage time, episode-level
OR 1.03 per 5 days(0.95–1.11)
Mean storage time, patient-level
OR 1.02(0.95–1.10)
Weighted mean storage time, patient-level
OR 1.02(0.95–1.10)
Maximum storage time, patient-level
OR 1.06(0.98–1.14)
Scalar Age of Blood Index, patient-level
OR 0.99(0.96–1.03)
Per 5 days, as printed
- Patients with postoperative infections
- 1025 (25.3%)
Observational data: associations, not effects.
Original publication
Association Between Storage Time of Transfused Red Blood Cells and Infection After Clean-contaminated Surgery: A Retrospective Cohort Study. Ann Surg. Published 20 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →