Cardiothoracic & vascular anesthesia

Association of Preoperative Renal-Resistive Index With Long-term Renal and Cardiovascular Outcomes After Cardiac Surgery

J Cardiothorac Vasc AnesthPublished Observational cohort study

Authors' conclusion

Elevated preoperative RRI is associated with persistent renal dysfunction, MAKE, and MACE after cardiac surgery.

Study context

Population
Adults undergoing cardiac surgery, university hospital; Renal-resistive index (RRI) measured the day before surgery
Participants
96 adults
Exposure
Elevated preoperative RRI vs non-elevated RRI
Outcome
Persistent renal dysfunction, MAKE and MACE by elevated RRI (adjusted for baseline renal function and HF)
Follow-up
5 years
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Elevated RRI vs Non-elevated RRIHazard ratio (95% CI)
Persistent renal dysfunction
5.82(1.71–19.9)
MAKE
4.21(1.59–11.1)
MACE
2.81(1.03–7.65)
Persistent renal dysfunction, all patients
25 (26%)
Major adverse kidney events (MAKE), all patients
34 (35%)
Major adverse cardiovascular events (MACE), all patients
28 (29%)

Observational data: associations, not effects.

Further findings

OutcomeMedian RRIP value
Preoperative RRI in patients with vs without each outcome · 5 yearsPersistent renal dysfunction vs No persistent renal dysfunction0.78 [IQR, 0.74-0.82] v 0.70 [0.66-0.77]P = 0.001
Preoperative RRI in patients with vs without each outcome · 5 yearsMAKE vs No MAKE · IQR0.77 [0.72-0.81] v 0.68 [0.65-0.76]P = 0.002
Preoperative RRI in patients with vs without each outcome · 5 yearsMACE vs No MACE · IQR0.77 [0.72-0.81] v 0.70 [0.66-0.77]P = 0.006

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association of Preoperative Renal-Resistive Index With Long-term Renal and Cardiovascular Outcomes After Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 28 October 2023. doi:10.1053/j.jvca.2023.10.035

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