Cardiothoracic & vascular anesthesia
Association of Preoperative Renal-Resistive Index With Long-term Renal and Cardiovascular Outcomes After Cardiac Surgery
Authors' conclusion
Elevated preoperative RRI is associated with persistent renal dysfunction, MAKE, and MACE after cardiac surgery.
Study context
- Population
- Adults undergoing cardiac surgery, university hospital; Renal-resistive index (RRI) measured the day before surgery
- Participants
- 96 adults
- Exposure
- Elevated preoperative RRI vs non-elevated RRI
- Outcome
- Persistent renal dysfunction, MAKE and MACE by elevated RRI (adjusted for baseline renal function and HF)
- Follow-up
- 5 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Elevated RRI vs Non-elevated RRIHazard ratio (95% CI)
Persistent renal dysfunction
5.82(1.71–19.9)
MAKE
4.21(1.59–11.1)
MACE
2.81(1.03–7.65)
- Persistent renal dysfunction, all patients
- 25 (26%)
- Major adverse kidney events (MAKE), all patients
- 34 (35%)
- Major adverse cardiovascular events (MACE), all patients
- 28 (29%)
Observational data: associations, not effects.
Further findings
| Outcome | Median RRI | P value |
|---|---|---|
| Preoperative RRI in patients with vs without each outcome · 5 yearsPersistent renal dysfunction vs No persistent renal dysfunction | 0.78 [IQR, 0.74-0.82] v 0.70 [0.66-0.77] | P = 0.001 |
| Preoperative RRI in patients with vs without each outcome · 5 yearsMAKE vs No MAKE · IQR | 0.77 [0.72-0.81] v 0.68 [0.65-0.76] | P = 0.002 |
| Preoperative RRI in patients with vs without each outcome · 5 yearsMACE vs No MACE · IQR | 0.77 [0.72-0.81] v 0.70 [0.66-0.77] | P = 0.006 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association of Preoperative Renal-Resistive Index With Long-term Renal and Cardiovascular Outcomes After Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 28 October 2023. doi:10. 1053/ j. jvca. 2023. 10. 035
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