Association of Relative Dysglycemia With Hospital Mortality in Critically Ill Patients: A Retrospective Study*
Authors' conclusion
Mortality significantly increased when GR during the first 24 hours after ICU admission deviated from between 0.69 and 1.25.
Study context
- Population
- Adult critically ill patients admitted urgently to an urban tertiary hospital ICU, January 2016–March 2022
- Participants
- 1,700 patients
- Exposure
- Nonsurvivors vs Survivors
- Outcome
- In-hospital mortality by maximum and minimum glycemic ratio (GR: max/min blood glucose ÷ HbA1c-derived average glucose)
- Follow-up
- First 24 hours after ICU admission
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
In-hospital mortality vs GR
- In-hospital mortality
- 16.9%
- Maximum glycemic ratio (GR): J-shaped association with mortality; mortality trough at maximum GR
- ≈1.12
- Maximum GR threshold for increased adjusted OR for mortality
- 1.25
- Minimum GR: U-shaped relationship with mortality; mortality trough at minimum GR
- ≈0.81
- Minimum GR lower threshold for increased adjusted OR for mortality
- 0.69
Observational data: associations, not effects.
Further findings
Maximum and minimum GR, nonsurvivors vs survivors
- Nonsurvivors had a higher maximum GR, with no significant difference in minimum GR
Original publication
Association of Relative Dysglycemia With Hospital Mortality in Critically Ill Patients: A Retrospective Study*. Crit Care Med. Published 24 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →