Cardiothoracic & vascular anesthesia
Association of Sarcopenia, as Defined Based on the Skeletal Muscle Index, With Mortality and Morbidity After Cardiac Surgery: A Retrospective Cohort Study
Main finding · All-cause mortalityResult — go to the resultAdjusted hazard ratio 1.80 95% CI 1.04–3.11Authors' conclusion
Sarcopenia, defined by the skeletal muscle index, is associated with all-cause mortality and major morbidity after cardiac surgery
Study context
- Population
- Adult Chinese patients undergoing cardiac surgery (CABG, valve, combined or aortic surgery), January 2019–August 2022968 followed
- Participants
- 986 patients
- Exposure
- Sarcopenia vs nonsarcopenia
- Outcome
- All-cause mortality
Methodological detailsobservational
- Observational
Main finding
As reported in the abstract
median follow-up 2.00 years (1.06 to 2.90)
Adjusted hazard ratio
1.80
95% CI 1.04–3.11
P = 0.034
Sarcopenia vs Nonsarcopenia
aHR 1.80 (95% CI 1.04–3.11); P = 0.034
- Deaths during follow-up (overall)
- 76
Observational data: associations, not effects.
Secondary outcomes
| Outcome | aOR (95% CI) | P value | |
|---|---|---|---|
| Major morbidityMultivariate analysis | 2.21 (1.52∼3.22) | P < 0.001 | |
| 0.20.5125Adjusted odds ratio (log scale) |
- Major morbidity — Patients with major morbidity (overall)
- 199 (20.6%)
Original publication
Association of Sarcopenia, as Defined Based on the Skeletal Muscle Index, With Mortality and Morbidity After Cardiac Surgery: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 20 January 2024. doi:10.
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