Haemodynamics, fluids & transfusion

Association of postoperative anaemia with prolonged hospital length of stay after upper gastrointestinal cancer surgery: a single-centre retrospective cohort study✰

BJA OpenPublished Retrospective cohort study

Main finding · Association of first-week Hb nadir with prolonged LOS (multivariable)Result — go to the resultOdds ratio 0.95 per g L-1 95% CI 0.92–0.98

Authors' conclusion

Postoperative Hb decline is independently associated with prolonged LOS after elective upper GI cancer surgery.

Study context

Population
Patients undergoing elective upper gastrointestinal (GI) cancer surgery at a tertiary hospital in Western Australia
Participants
111 patients
Exposure
Prolonged length of stay (LOS) vs expected LOS
  • Prolonged LOSn = 26
Outcome
Prolonged LOS (above procedure-specific median LOS); association with Hb
Methodological detailssingle-centre, multivariable logistic regression
  • Single-centre
  • Multivariable logistic regression

Main finding

As reported in the abstract

Association of first-week Hb nadir with prolonged LOS (multivariable)

Odds ratio

0.95 per g L-1

95% CI 0.92–0.98

P = 0.002

First-week Hb nadir
OR 0.95 per g L-1 (95% CI 0.92–0.98); P = 0.002

Per g L-1, as printed

Observational data: associations, not effects.

Further findings

Mean, g L-1

OutcomeProlonged LOSP value
Intraoperative Hb106.5 (SD 17.9)P = 0.021
Hb on POD 1 · postoperative day 1100.1 (SD 17.3)P = 0.002
First-week Hb nadir89.3 (SD 17.0)P < 0.001

Safety

OutcomeP value
ReoperationP = 0.001
Unplanned ICU admissionP = 0.023

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association of postoperative anaemia with prolonged hospital length of stay after upper gastrointestinal cancer surgery: a single-centre retrospective cohort study✰. BJA Open. Published 3 August 2026. doi:10.1016/j.bjao.2026.100648

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