Cardiothoracic & vascular anesthesia
Blood Glucose Variability and Postoperative Organ Function in Coronary Artery Bypass Grafting: A Prospective Cohort Study of Microcirculatory Perfusion and Oxygenation
Authors' conclusion
Postoperative BGV and early microcirculatory impairment are associated with high risk for organ dysfunction in CABG patients.
Study context
- Population
- Adults undergoing elective on-pump coronary artery bypass grafting (CABG)
- Participants
- 51 adults
- Outcome
- Organ dysfunction, defined by Cardiac Surgery Score (CASUS) >6.5
- Follow-up
- POD 1
Methodological detailstwo-centre (tertiary academic and secondary cardiac hospital)
- Two-centre (tertiary academic and secondary cardiac hospital)
Main finding
As reported in the abstract
Discrimination of organ dysfunction (CASUS >6.5) on POD 1 by postoperative BGV metrics and admission microcirculation
- Postoperative blood glucose variability (BGV) SD, AUC
- 0.952
- Postoperative BGV coefficient of variation (CV), AUC
- 0.931
- Postoperative mean amplitude of glycemic excursions, AUC
- 0.936
- Optimal SD cutoff (mg/dL)
- 56.98
- SD cutoff sensitivity
- 100%
- SD cutoff specificity
- 91.5%
- Lower admission proportion of perfused vessels, AUC
- 0.963
- Lower admission perfused vessel density, AUC
- 0.918
Observational data: associations, not effects.
Further findings
Correlation of perioperative BGV (CV) with microcirculation and lactate
- CV vs proportion of perfused vessels, r (p < 0.05)
- −0.309
- CV vs lactate, r (p < 0.05)
- 0.280
Original publication
Blood Glucose Variability and Postoperative Organ Function in Coronary Artery Bypass Grafting: A Prospective Cohort Study of Microcirculatory Perfusion and Oxygenation. J Cardiothorac Vasc Anesth. Published 29 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →