Respiratory failure & ventilation
Combined cardiac, lung, and diaphragm ultrasound for predicting weaning failure during spontaneous breathing trial
Authors' conclusion
LUS and diaphragm ultrasound can help to predict weaning failure in patients undergoing an SBT with low-level pressure support. An antero-lateral LUS score > 7 and DTF < 31% during the SBT were associated with weaning failure.
Study context
- Population
- Critically ill patients on invasive mechanical ventilation (MV) > 48 h readied for their first spontaneous breathing trial (SBT) (2-h, low-level pressure support)15 weaning failure
- Participants
- 51 patients
- Comparison
- Lung ultrasound (LUS), TTE and diaphragm ultrasound for predicting weaning failure
- Outcome
- Weaning failure (failure of SBT, re-intubation, or non-invasive ventilation)
- Follow-up
- Within 48 h
Methodological detailsprospective
- Prospective
Performance
As reported in the abstract
Prediction of weaning failure · during the SBT
| Test or model | AUC |
|---|---|
| Diaphragm thickening fraction (DTF) | 0.678 |
| Global LUS score | 0.719 |
| Antero-lateral LUS score | 0.721 |
AUC
Diaphragm thickening fraction (DTF)0.678
Global LUS score0.719
Antero-lateral LUS score0.721
Further findings
LUS scores during the SBT, failed vs successful
- Global, anterior and antero-lateral LUS scores higher in the failed group than in the successful group
Correlation of LUS scores with average E/e' ratio · during the SBT
- No correlation between LUS scores and average E/e' ratio
Original publication
Combined cardiac, lung, and diaphragm ultrasound for predicting weaning failure during spontaneous breathing trial. Ann Intensive Care. Published 20 April 2024. doi:10.
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