Cardiothoracic & vascular anesthesia
Combined pectoralis and serratus anterior plane blocks with or without liposomal bupivacaine for minimally invasive thoracic surgery: A randomized clinical trial
Primary result · Total OBAS, POD 1-3Result — go to the resultGeometric mean ratio 0.93 95% CI 0.76–1.14Authors' conclusion
Liposomal bupivacaine did not improve OBAS during the initial postoperative three days following minimally invasive thoracic procedures.
Study context
- Population
- Adults scheduled for robotically or video-assisted thoracic surgery with combined ultrasound-guided pectoralis II and serratus anterior plane blockanalysed
- Participants
- 189 adults
- Comparison
- Liposomal bupivacaine vs Bupivacaine
- Liposomal bupivacainen = 95
- Bupivacainen = 94reference
- Primary endpoint
- Overall benefit of analgesia score (OBAS)
- Follow-up
- Postoperative days 1-3
Primary result
Total OBAS, POD 1-3 · first three postoperative days
Geometric mean ratio
0.93
95% CI 0.76–1.14
P = 0.485
Treatment vs Control
geometric mean ratio 0.93 (95% CI 0.76–1.14); P = 0.485
As reported in the abstract
Further findings
Respiratory mechanics, total opioid consumption, pain scores
- No observed treatment effect; average pain scores low in both groups
Original publication
Combined pectoralis and serratus anterior plane blocks with or without liposomal bupivacaine for minimally invasive thoracic surgery: A randomized clinical trial. J Clin Anesth. Published 18 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →