Sepsis & infection

Comorbid burden at intensive care unit (ICU) admission in COVID‐19 compared to sepsis and acute respiratory distress syndrome

Acta Anaesthesiol ScandPublished Registry-based cohort study

Authors' conclusion

Patients admitted to ICU with sepsis or ARDS carry a heavier burden of comorbidity and high age than patients admitted with COVID-19.

Study context

Population
Adults admitted to Swedish ICUs
Participants
7,382 / 22,354 / 2,776
Exposure
COVID-19 vs sepsis and vs acute respiratory distress syndrome (ARDS) ICU admissions
  • COVID-19n = 7,382
  • Sepsisn = 22,354
  • ARDSn = 2,776
Outcome
Adjusted odds for comorbidities, sex and age by diagnostic category (COVID-19 vs sepsis; COVID-19 vs ARDS)
Methodological detailsnationwide, multivariable logistic regression
  • Nationwide
  • Multivariable logistic regression

Main finding

As reported in the abstract

Adjusted associations of risk factors with ICU admission diagnosis
  • COVID-19 vs sepsis: most comorbidities and age more strongly associated with sepsis admission
  • COVID-19 vs sepsis: male sex, type 2 DM and asthma more strongly associated with COVID-19 admission
  • COVID-19 vs sepsis: no difference for chronic renal failure and obesity
  • COVID-19 vs ARDS: most risk factors more strongly associated with ARDS admission
  • COVID-19 vs ARDS: male sex, type 2 DM, chronic renal failure and obesity more strongly associated with COVID-19 admission
  • COVID-19 vs ARDS: hypertension, COPD and asthma not different

Observational data: associations, not effects.

Original publication

Comorbid burden at ICU admission in COVID‐19 compared to sepsis and acute respiratory distress syndrome. Acta Anaesthesiol Scand. Published 26 August 2024. doi:10.1111/aas.14514

Composed by AI from the published abstract and checked against it. How Briefs are made →

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