Cardiothoracic & vascular anesthesia
Comparative effects of variable versus conventional volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in thoracic surgery patients: A randomized controlled clinical trial
Authors' conclusion
In thoracic surgery patients under OLV, V-VCV did not improve oxygenation or respiratory system mechanics compared to C-VCV.
Study context
- Population
- Patients undergoing thoracic surgery under one-lung ventilation (OLV)75 completed and analysed
- Participants
- 78 patients
- Comparison
- Variable vs conventional volume-controlled OLV
- V-VCVn = 39
- Conventional volume-controlled ventilation (C-VCV)n = 39reference
- Primary endpoint
- Pressure of arterial oxygen (PaO2)
- Follow-up
- 20 min after the start of OLV
Primary result
As reported in the abstract
Mean difference
1.3
95% CI −8.2 to 5.5
P = 0.700
By group
V-VCV vs C-VCV
mean difference 1.3 (95% CI −8.2 to 5.5); P = 0.700
Further findings
Intraoperative gas exchange, rescue maneuvers for desaturation and hypercapnia, hospital free days at day 30
- Did not differ between groups
Safety
Intraoperative adverse events, postoperative pulmonary and extra-pulmonary complications
- Did not differ between groups
Original publication
Comparative effects of variable versus conventional volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in thoracic surgery patients: A randomized controlled clinical trial. J Clin Anesth. Published 6 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →