Respiratory failure & ventilation
Comparison of mainstream end tidal carbon dioxide on Y-piece side versus patient side of heat and moisture exchanger filters in critically ill adult patients: a prospective observational study
Main finding · Accuracy difference (Y-piece vs patient side)Result — go to the resultAccuracy difference - 0.14 mmHg two-sided 90% CI - 0.58 to 0.29Authors' conclusion
The accuracy of mainstream EtCO2 measurements on the Y-piece side of HMEF was noninferior to that on the patient side in critically ill adults.
Study context
- Population
- Critically ill adults receiving mechanical ventilation with heat and moisture exchanger filter (HMEF)
- Participants
- 37 adults
- Exposure
- Mainstream EtCO2 on Y-piece side vs patient side of HMEF
- Outcome
- Accuracy of EtCO2 (absolute difference between PaCO2 and EtCO2); non-inferiority margin + 1 mmHg
Methodological detailsnon-inferiority, July 2019 to December 2019
- Non-inferiority
- July 2019 to December 2019
Main finding
Accuracy difference (Y-piece vs patient side)
Accuracy difference
- 0.14 mmHg
two-sided 90% CI - 0.58 to 0.29
P < 0.001 for non-inferiority
As reported in the abstract
Observational data: associations, not effects.
Further findings
Agreement between PaCO2 and EtCO2 (Bland-Altman 95% limits of agreement)
- Limits of agreement similar on both sides of HMEF
Original publication
Comparison of mainstream end tidal carbon dioxide on Y-piece side versus patient side of heat and moisture exchanger filters in critically ill adult patients: a prospective observational study. J Clin Monit Comput. Published 3 August 2022. doi:10.
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