Cardiothoracic & vascular anesthesia
Comparison of Perioperative Outcomes for Transfusion of Hemoconcentrated Bypass Versus Cell Saver Blood in Cardiac Surgical Patients
Main finding · Postoperative ICU RBC transfusionsResult — go to the resultMean difference −0.37 95% CI −0.78 to 0.04Authors' conclusion
There is no significant difference in postoperative blood transfusion rates in hemoconcentrated versus cell saver blood usage in cardiac surgery patients.
Study context
- Population
- Adults (>18 y) undergoing elective open-heart surgery with CPB, tertiary care centre, January 2015 to January 2018; emergencies, off-pump, transplants, reoperations and second bypass excluded735 analysed after matching
- Participants
- 744 adults
- Comparison
- Hemoconcentrated bypass blood vs cell saver blood
- Outcome
- Perioperative transfusion of packed RBC and blood products
Methodological detailssingle-centre, propensity-score matched, retrospective chart review
- Single-centre
- Propensity-score matched
- Retrospective chart review
Main finding
Postoperative ICU RBC transfusions
Mean difference
−0.37
95% CI −0.78 to 0.04
Hemoconcentrated vs Cell saver
mean difference −0.37 (95% CI −0.78 to 0.04)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Mean difference (95% CI) | |
|---|---|---|
| Postoperative ICU platelets | −0.01 (−0.11 to 0.09) | |
| Postoperative ICU FFP | −0.08 (−0.19 to 0.03) | |
| −0.2−0.100.1Difference (linear scale) |
Intensive care unit (ICU) LOS, hospital LOS, surgical site infections and other outcomes
- No significant differences in bivariate- and covariate-adjusted models
Original publication
Comparison of Perioperative Outcomes for Transfusion of Hemoconcentrated Bypass Versus Cell Saver Blood in Cardiac Surgical Patients. J Cardiothorac Vasc Anesth. Published 30 January 2025. doi:10. 1053/ j. jvca. 2025. 01. 035
Composed by AI from the published abstract and checked against it. How Briefs are made →