Cardiothoracic & vascular anesthesia

Comparison of Perioperative Outcomes for Transfusion of Hemoconcentrated Bypass Versus Cell Saver Blood in Cardiac Surgical Patients

J Cardiothorac Vasc AnesthPublished Retrospective case-control study

Main finding · Postoperative ICU RBC transfusionsResult — go to the resultMean difference −0.37 95% CI −0.78 to 0.04

Authors' conclusion

There is no significant difference in postoperative blood transfusion rates in hemoconcentrated versus cell saver blood usage in cardiac surgery patients.

Study context

Population
Adults (>18 y) undergoing elective open-heart surgery with CPB, tertiary care centre, January 2015 to January 2018; emergencies, off-pump, transplants, reoperations and second bypass excluded735 analysed after matching
Participants
744 adults
Comparison
Hemoconcentrated bypass blood vs cell saver blood
Outcome
Perioperative transfusion of packed RBC and blood products
Methodological detailssingle-centre, propensity-score matched, retrospective chart review
  • Single-centre
  • Propensity-score matched
  • Retrospective chart review

Main finding

Postoperative ICU RBC transfusions

Mean difference

−0.37

95% CI −0.78 to 0.04

Hemoconcentrated vs Cell saver
mean difference −0.37 (95% CI −0.78 to 0.04)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeMean difference (95% CI)
Postoperative ICU platelets−0.01 (−0.11 to 0.09)
Postoperative ICU FFP−0.08 (−0.19 to 0.03)

Intensive care unit (ICU) LOS, hospital LOS, surgical site infections and other outcomes

No significant differences in bivariate- and covariate-adjusted models

Original publication

Comparison of Perioperative Outcomes for Transfusion of Hemoconcentrated Bypass Versus Cell Saver Blood in Cardiac Surgical Patients. J Cardiothorac Vasc Anesth. Published 30 January 2025. doi:10.1053/j.jvca.2025.01.035

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