Comparison of the bispectral indices of patients receiving remimazolam and propofol for general anesthesia: a randomized crossover trial
Authors' conclusion
The trial indicated that remimazolam maintained a higher BIS level than propofol.
Study context
- Population
- Patients requiring multiple hysteroscopic surgerycompleted the study
- Participants
- 17 patients
- Comparison
- Remimazolam vs propofol for GA
- Primary endpoint
- BIS values
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
- Remimazolam vs Propofol: P = 0.001
- Remimazolam vs Propofol: P < 0.001
Secondary outcomes
Intraoperative conditions and recovery
- Smaller intraoperative diastolic BP and heart rate changes and faster recovery with remimazolam
Safety
- Fewer adverse reactions and less injection pain, but greater incidence of intraoperative body movement and hiccups with remimazolam
Original publication
Comparison of the bispectral indices of patients receiving remimazolam and propofol for general anesthesia: a randomized crossover trial. Anaesth Crit Care Pain Med. Published 15 March 2024. doi:10.
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