Anesthetic drugs & techniques

Comparison of the effect of isoflurane and propofol on liver regeneration after donor hepatectomy - A randomized controlled trial

J Clin AnesthPublished Randomised controlled trial

Authors' conclusion

Administering propofol or isoflurane may not have differential effect on liver regeneration after donor hepatectomy.

Study context

Population
Donors undergoing donor hepatectomy
Participants
60 donors
Comparison
Isoflurane vs propofol for anaesthesia maintenance
Methodological detailspilot
  • Pilot

Primary result

As reported in the abstract

RgLV on POD14 · POD 14

Regeneration liver volume (RgLV) on POD14 comparable in two groups

449.3(170) & 437.8 (177.8) cm3

Mean Difference (MD), 95% CI; p

−11.904

−101.83, 78.03p = 0.79

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Comparison of the effect of isoflurane and propofol on liver regeneration after donor hepatectomy - A randomized controlled trial. J Clin Anesth. Published 9 May 2025. doi:10.1016/j.jclinane.2025.111859

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