Cardiothoracic & vascular anesthesia
Comparison of the Point‐Of‐Care Coagulation Device Quantra With the TEG‐5000 for Congenital Cardiac Surgery—A Pilot Study
Authors' conclusion
Despite weaknesses in correlation and agreement both VET devices suggested appropriate coagulation management based on the simulated transfusion algorithms. Quantra and TEG-5000 are not interchangeable and none of them can be considered as "the gold standard".
Study context
- Population
- Children (0–8 years) undergoing congenital cardiac surgery with cardiopulmonary bypass (CPB), Stanford Medicine Children's Healthincluded in the analysis
- Participants
- 40 children
- Exposure
- Quantra vs TEG-5000
- Outcome
- Correlation of Quantra with TEG-5000 and Clauss Fibrinogen
- Follow-up
- On CPB during rewarming (T1) and after blood components and coagulation factors (T2)
Methodological detailssingle-centre, Consecutive screening October 2022 to May 2023: 289 surgeries, 97 met inclusion criteria, 63 consented
- Single-centre
- Consecutive screening October 2022 to May 2023: 289 surgeries, 97 met inclusion criteria, 63 consented
Main finding
As reported in the abstract
Correlation of Quantra with Clauss Fibrinogen and TEG-5000
- Correlation of Quantra/Clauss Fibrinogen "moderate"
- Correlation of Quantra/TEG-5000 parameters ranged from "weak" to "very strong"
Observational data: associations, not effects.
Further findings
Agreement of post hoc simulated transfusion algorithm with clinical management · post hoc
FFP agreement
Fibrinogen agreement
Platelets agreement
Agreement for normal and abnormal results
- Levels of agreement ranged
- 15% to 97%
Original publication
Comparison of the Point‐Of‐Care Coagulation Device Quantra With the TEG‐5000 for Congenital Cardiac Surgery—A Pilot Study. Paediatr Anaesth. Published 17 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →