Cardiothoracic & vascular anesthesia
Comparison of the Quantra QPlus and Rotational Thromboelastometry (ROTEM) Goal-Directed Transfusion Protocols in Cardiothoracic Surgery Patients: A Prospective Observational Study
Authors' conclusion
ROTEM-guided and Quantra-guided transfusion did not correspond in this patient group, and agreement was moderate at best.
Study context
- Population
- Adults undergoing elective CPB surgery with a ROTEM test, Maastricht University Medical Center, The Netherlands
- Participants
- 100 samples
- Exposure
- Quantra QPlus vs ROTEM goal-directed transfusion protocols
- Outcome
- Agreement (Cohen κ)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Overall transfusion: poor agreement
0.174
Fibrinogen transfusion: poor agreement
0.300
Cutoffs fibrinogen clot stiffness (Quantra) vs EXTEM A10 (ROTEM): poor agreement
0.160
Fibrinogen clot stiffness vs FIBTEM A10: moderate agreement
0.731
Observational data: associations, not effects.
Further findings
Transfusion advice in non-bleeders and bleeders
- Quantra QPlus protocol advises transfusion in many non-bleeders
- In a small group with clinically relevant blood loss, Quantra QPlus advised transfusion whereas ROTEM did not
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Comparison of the Quantra QPlus and ROTEM Goal-Directed Transfusion Protocols in Cardiothoracic Surgery Patients: A Prospective Observational Study. J Cardiothorac Vasc Anesth. Published 7 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →