Continuous measurement of carotid-femoral pulse wave velocity (PWVcf.) during general anaesthesia using Doppler: a preliminary study
Authors' conclusion
Measurement of PWV under GA using carotid and femoral Doppler is a feasible method to continuously assess arterial stiffness under general anaesthesia.
Study context
- Population
- Patients scheduled for surgery with general anaesthesia (GA), December 2022 to February 202341 successful pulse wave velocity (PWV) measurements
- Participants
- 43 patients
- Exposure
- PWV at awakening vs during GA; CVR+ vs CVR- patients
- Outcome
- Feasibility of continuous carotid-femoral PWV monitoring with Doppler during GA (successful PWV measurements)
Methodological detailspreliminary study
- Preliminary study
Main finding
As reported in the abstract
Successful PWV measurements
Successful PWV measurements
41
95%
Observational data: associations, not effects.
Further findings
PWVGA by cardiovascular risk
P < 0.01
α-angle by cardiovascular risk
P < 0.001
α x PWVGA product by cardiovascular risk
P < 0.001
| Outcome | P value |
|---|---|
| PWV at awakening (PWVAW) vs during GA (PWVGA)Difference vanished after matching MAP levels | P < 0.0001 |
- PWV at awakening (PWVAW) vs during GA (PWVGA) — Correlation PWVAW vs PWVGA (r)
- 0.88
- PWV at awakening (PWVAW) vs during GA (PWVGA) — Correlation at the same MAP levels (r)
- 0.97
- PWVGA by cardiovascular risk — AUC for cardiovascular risk
- 0.80 [0.65-0.95]
- α-angle by cardiovascular risk — AUC for cardiovascular risk
- 0.83 [0.69-0.96]
- α x PWVGA product by cardiovascular risk — AUC for cardiovascular risk
- 0.86 [0.74-0.97]
- PWV at awakening (PWVAW) vs during GA (PWVGA): PWVAW 8.1 m.s-1
- PWV at awakening (PWVAW) vs during GA (PWVGA): PWVGA 7.4 m.s-1
- PWVGA by cardiovascular risk: 95%CI
- α-angle by cardiovascular risk: 95%CI
- α x PWVGA product by cardiovascular risk: 95%CI
Original publication
Continuous measurement of carotid-femoral pulse wave velocity (PWVcf.) during general anaesthesia using Doppler: a preliminary study. J Clin Monit Comput. Published 13 March 2025. doi:10.
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