Cumulative impact of hypotension during intermittent hemodialysis on kidney recovery in critically ill patients with AKI-D
Authors' conclusion
Our study revealed that IHD-related hypotension during hospitalization has a cumulative negative impact on kidney recovery in AKI-D survivors.
Study context
- Population
- AKI-D survivors who received intermittent hemodialysis in the ICUs of a tertiary care hospital in Korea, January 2018 to February 20241,791 intermittent hemodialysis (IHD) sessions
- Participants
- 209 survivors
- Exposure
- Number of intradialytic hypotension episodes during IHD
- Outcome
- Dialysis dependence (kidney recovery)
- Follow-up
- Hospital discharge
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Dialysis dependence
Odds ratio (95 % CI)
Number of IDHper IDH episode
1.56(1.16–2.22)
≥3 IDH episodes vs No IDH
9.41(2.41–41.69)
- Dialysis-dependent at hospital discharge (all patients)
- 43.1 %
Observational data: associations, not effects.
Further findings
IHD sessions per patient
- Median IHD sessions per patient: 7 (IQR 3-11)
Incidence of IDH per patient
- IDH incidence per patient
- 16.8 %
Risk factors for IDH (per-session analysis)
- Target ultrafiltration rate an independent risk factor for IDH occurrence
Original publication
Cumulative impact of hypotension during intermittent hemodialysis on kidney recovery in critically ill patients with AKI-D. J Crit Care. Published 30 October 2024. doi:10.
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