A pilot feasibility study of continuous cardiac output and blood pressure monitoring during intermittent hemodialysis in patients recovering from severe acute kidney injury
Authors' conclusion
CI often, repeatedly, and markedly decreased during IHD. Such decreases were not detected by MAP monitoring and were extreme in some patients.
Study context
- Population
- Patients recovering from severe acute kidney injury (AKI) undergoing intermittent hemodialysis (IHD) after transition from continuous renal replacement therapy (CRRT)
- Participants
- 10 patients
- Outcome
- Changes in cardiac output and BP during IHD (continuous hemodynamic monitoring, ClearSight System)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Intradialytic reductions in cardiac index
- Episodes of severe CI reduction
- 119
- Episodes of moderate CI reduction
- 286
- Median time with severe CI reduction, min [range]
- 8.2 [2.1-115.8]
- Median time with moderate CI reduction, min [range]
- 49.5 [21.6-57.5]
- Patients with severe CI reductions
- 9 of 10
- Patients with severe CI reductions lasting >2 h
- 3
- MAP increased or stable, % of measurements, regardless of CI changes
- >78 %
Further findings
CI change during moderate blood volume (BV) decrease
- CI change, L/min/m²
- −1.14
- P
- P < 0.001
CI change with high NUF rate
- CI change, L/min/m²
- −0.57
- P
- P < 0.001
Original publication
A pilot feasibility study of continuous cardiac output and blood pressure monitoring during intermittent hemodialysis in patients recovering from severe acute kidney injury. J Crit Care. Published 13 April 2025. doi:10.
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