Daily point-of-care ultrasound-assessment of central venous catheter-related thrombosis in critically ill patients: a prospective multicenter study
Authors' conclusion
CRT is a frequent complication. It can occur as soon as the CVC is placed and mostly during the first week following catheterization. Half of the thromboses are small but one-third are extensive. They are often non-progressive and may be resolved after CVC removal.
Study context
- Population
- Critically ill patients with a central venous catheter (CVC) in 28 intensive care units (ICUs)
- Participants
- 1,262 patients · 28 ICUs
- Outcome
- Occurrence and evolution of CVC-related thrombosis (CRT) from CVC insertion to removal
Methodological detailsmulticentre, daily duplex ultrasound, Duplex ultrasound daily from CVC insertion until at least 3 days after removal or before ICU discharge; diameter > 7 mm considered extensive
- Multicentre
- Daily duplex ultrasound
- Duplex ultrasound daily from CVC insertion until at least 3 days after removal or before ICU discharge; diameter > 7 mm considered extensive
Main finding
As reported in the abstract
Incidence of CRT
- CRT incidence
- 16.9% (95% CI 14.8-18.9%)
- Median time from CVC insertion to CRT onset, days
- 4 (2-7)
- CRTs on first day of CVC insertion
- 12%
- CRTs within 7 days of CVC insertion
- 82%
- CRT diameter > 5 mm
- 48%
- CRT diameter > 7 mm (extensive)
- 30%
Observational data: associations, not effects.
Further findings
- ICU LOS longer with CRT; mortality not different
Original publication
Daily point-of-care ultrasound-assessment of central venous catheter-related thrombosis in critically ill patients: a prospective multicenter study. Intensive Care Med. Published 9 March 2023. doi:10.
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