Cardiothoracic & vascular anesthesia
Delirium After Transcatheter Aortic Valve Replacement: Incidence, Predictive Factors, and 1-Year Functional and Cognitive Outcomes
Authors' conclusion
POD is a serious complication after TAVR, particularly in patients with cognitive impairments or those undergoing nontransfemoral access.
Study context
- Population
- Elderly patients undergoing transcatheter aortic valve replacement (TAVR) via transfemoral or alternative access, single-centre tertiary university hospital
- Participants
- 201 patients
- Exposure
- Postoperative delirium (POD) vs no POD after TAVR
- Outcome
- Incidence of POD after TAVR
- Follow-up
- 5 days postoperatively
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Incidence of POD
Incidence of POD
21.9%
Observational data: associations, not effects.
Further findings
Independent predictors of POD (multivariate logistic regression)
| OR (95% CI) | ||
|---|---|---|
| Lower baseline MMSE | 0.81 (0.70–0.94) | |
| Elevated white blood cell count | 1.19 (1.01–1.41) | |
| Nontransfemoral access | 3.09 (1.36–7.02) | |
| 0.10.31310Odds ratio (log scale) |
| Outcome | HR | P value |
|---|---|---|
| Mortality · 1 yearPOD vs No POD | 2.73 | P = 0.03 |
Hospital LOS and functional recovery (Barthel Index)
- POD associated with prolonged hospital stays and impaired functional recovery at follow-up (lower Barthel Index)
Mini-Mental State Examination (MMSE) evolution over time
- No significant differences, indicating a likely preexisting cognitive vulnerability
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Delirium After Transcatheter Aortic Valve Replacement: Incidence, Predictive Factors, and 1-Year Functional and Cognitive Outcomes. J Cardiothorac Vasc Anesth. Published 31 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →