Cardiothoracic & vascular anesthesia
Transfemoral Versus Transcarotid Transcatheter Aortic Valve Replacement Under Locoregional Anesthesia: A Propensity-Matched Single-Center Analysis of 868 Patients
Authors' conclusion
TC-TAVR under locoregional anesthesia is a safe and effective alternative to TF-TAVR, with comparable mortality and neurologic outcomes.
Study context
- Population
- Patients undergoing TAVR, Reims University Hospital, France, January 2017–September 2023135 matched pairs analysed
- Participants
- 868 patients
- Exposure
- Transcarotid transcatheter aortic valve replacement (TC-TAVR) vs TF-TAVR
- TC-TAVRn = 161
- TF-TAVRn = 707reference
- Outcome
- All-cause mortality, and stroke or TIA
- Follow-up
- 30 days, 1 year, 2 years
Methodological detailssingle-centre, propensity-score matched, observational
- Single-centre
- Propensity-score matched
- Observational
Main finding
As reported in the abstract
All-cause mortality
All-cause mortality
2-year mortality
- Transcarotid (TC) vs transfemoral (TF): P = 0.447 — 30 days
- TC vs TF: P = 0.807 — 2 years
Observational data: associations, not effects.
Further findings
Stroke · not statistically significant · primary endpoint component
P = 0.214
Transient ischemic attack (TIA)
- No TIAs observed
Safety
Secondary complications (vascular, pacemaker implantation)
- Similarly distributed between groups
Original publication
Transfemoral Versus Transcarotid Transcatheter Aortic Valve Replacement Under Locoregional Anesthesia: A Propensity-Matched Single-Center Analysis of 868 Patients. J Cardiothorac Vasc Anesth. Published 21 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →