Cardiothoracic & vascular anesthesia
Retrospective Comparison of Surgical and Transcatheter Aortic Valve Replacement in Patients With Reduced Ejection Fraction: A Propensity-matched Analysis of Two Clinically Selected Populations
Authors' conclusion
While surgery may optimize survival after aortic valve replacement in patients with reduced EF
Study context
- Population
- Patients with severe aortic stenosis and reduced ejection fraction (EF) (<50%) undergoing aortic valve intervention, 2010 to 2023
- Participants
- 1,164 patients · 205 matched pairs
- Exposure
- Surgical aortic valve replacement (SAVR) vs transcatheter aortic valve replacement (TAVR)
- SAVRn = 240reference
- TAVRn = 924
- Outcome
- 30-day mortality and stroke
- Follow-up
- 30 days
Methodological detailspropensity-matched, single-centre, consecutive patients
- Propensity-matched
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
- 30-day mortality and stroke rates no different across groups
- Propensity-matched cohort
Observational data: associations, not effects.
Further findings
Mean pressure gradient · 1 year · higher in TAVR
P = 0.040
| Outcome | SAVR | TAVR | P value |
|---|---|---|---|
| EF · 1 yearSimilar between groups | 48% (IQR 41–53) | 53% (IQR 37–58) | P = 0.431 |
| Cumulative incidence of HF readmissionsHigher in TAVR, nonsignificant trend | P = 0.066 | ||
| Cumulative incidence of aortic valve reinterventionSimilar across groups | P = 0.564 | ||
| Kaplan-Meier survivalSignificantly lower in TAVR | P = 0.016 |
Safety
| Outcome | P value |
|---|---|
| PacemakersNonsignificant trend toward more in TAVR | P = 0.093 |
Paravalvular leak
- Significantly higher in the TAVR group
Original publication
Retrospective Comparison of Surgical and Transcatheter Aortic Valve Replacement in Patients With Reduced Ejection Fraction: A Propensity-matched Analysis of Two Clinically Selected Populations. J Cardiothorac Vasc Anesth. Published 23 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →