Depth of Anaesthesia Measured by Patient State Index ( Patient State Index (PSi) ) Does Not Correlate With Increased Seizure Duration During Electroconvulsive Therapy
Authors' conclusion
Pre-ictal PSi was not associated with EEG-seizure duration.
Study context
- Population
- Adults undergoing routine electroconvulsive therapy (ECT) at a Swedish university hospital, monitored with SedLine pEEG87 ECT sessions analysed
- Participants
- 37 adults
- Outcome
- Association between pre-ictal PSi (final value before ECT stimulus) and EEG-seizure duration (linear mixed-effects model adjusted for age and benzodiazepine or anticonvulsant use)
Methodological detailssingle-centre, clinical team blinded to PSi values
- Single-centre
- Clinical team blinded to PSi values
Main finding
As reported in the abstract
Pre-ictal PSi vs EEG-seizure duration
- No correlation between pre-ictal PSi and EEG-seizure duration
Observational data: associations, not effects.
Further findings
Baseline vs pre-ictal PSi
- Median baseline PSi (IQR 4)
- 94
- Median pre-ictal PSi (IQR 31; p < 0.001)
- 38
Effects of age and sex on PSi
- No significant effects of age or sex on pre-ictal PSi; significant difference between sexes on baseline PSi
EEG signal quality
- Artefact and EMG activity in the EEG signal minimal
Original publication
Depth of Anaesthesia Measured by Patient State Index ( PSi ) Does Not Correlate With Increased Seizure Duration During Electroconvulsive Therapy. Acta Anaesthesiol Scand. Published 18 November 2025. doi:10.
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